Endometriosis specialists
Years of experience in CO2 laser surgery
Scientific publications in peer review
Rectal endometriosis surgery
CEC: Endometriosis Center

Complex Endometriosis Center (CEC)

The center's mission is to care for, support and help women suffering from complex endometriosis. The CEC specializes in the management of rectal, sigmoidal, urinary and ovarian endometriosis with fertility preservation.

Successful management of endometriosis is a major challenge because this disease can cause intimacy, family, societal, professional, and even academic isolation for women suffering from it.

Endometriosis, a pathology with multiple implications!

Endometriosis is a chronic gynecological disease that affects around one in ten women of childbearing age, and its incidence can rise to 50% in cases of infertility. It is characterized by the presence of endometrial glands and stroma outside the uterine cavity, leading to pelvic pain and fertility problems.

This complex condition takes many forms and has numerous disabling repercussions on women's health.

CEC represents a reference alternative in the treatment of the four main forms of endometriosis:

  • Deep Endometriosis This is the most severe form. Endometriotic tissue deeply infiltrates the affected organ, possibly affecting the rectum, bladder, vagina, pelvic nerves or other abdominal anatomical structures.
  • Internal endometriosis: Also known as adenomyosis, this is the growth of endometrial tissue inside the muscle of the uterus.
  • Ovarian endometriosis This form is characterized by the presence of blood-filled cysts, called endometriomas, within the ovaries.
  • Peritoneal endometriosis Endometriosis of the peritoneum: Here, endometriotic tissue is deposited on the peritoneum, the thin layer of tissue covering the pelvic organs.

Each type of pathology presents specific symptoms, making the diagnosis and treatment of endometriosis particularly delicate. Appropriate management and increased awareness are therefore essential to improve the quality of life of women affected.

  • The CEC is proud to have taken part in this research, which is now being applied to scientific studies on new molecules for the treatment of endometriosis.

  • Céline and her son Mathias were able to complete the planned course. Many of you supported them in this courageous challenge. The CEC salutes and supports this initiative in aid of the Manoléta association, which takes part day after day, site after site, in the fight against Endometriosis.

  • Presentation on Shaving on March 6, 2024 in LondonProfessor DONNEZ spoke on March 6, 2024 as a recognized surgeon in the surgical management of endometriosis. He presented to the London team his knowledge of the surgical technique of shaving and the results obtained from the

  •                The month of March is marked by THE 20th EUROPEAN WEEK OF PREVENTION AND INFORMATION ON ENDOMETRIOSIS: MARCH 4-10, 2024 The Manoléta association is behind a dedicated event for healthcare professionals, which took place on March 9, 2024.

  • The 1st edition of the ENDOSUD day took place on December 15, 2023 at the Aix-en-Provence Convention Center.this day, organized with the support of ARS PACA, was aimed at healthcare professionals involved in the care of endometriosis sufferers. 

  • Training in diagnosis, management and referral of young girls with suspected endometriosis for national education teams The CEC is involved in training school doctors and nurses throughout the Vaucluse department.

  • Treatment of Caesarean section scar dehiscence CEC has recognized expertise in the treatment of Caesarean section scar dehiscence. This iatrogenic pathology, still little known and poorly defined, has recently been the subject of a consensus among experts, resulting in

  • "In 2019 and 2020, the CEC was the first center to be able to offer a GnRH antagonist, linzagolix, in clinical trials published in 2021 and 2022. This molecule has significantly reduced adenomyosis symptoms and uterine volume. We are proud to present

  •        For women's health The CEC is involved in coordinating the endometriosis care pathway. Amandine Poudou, the CEC's midwife coordinator, has just published a manuscript describing the midwife's role in screening consultations, in coordination within the referral center and in the management of endometriosis.

  • From October 1 to 4, the European Society for Gynecological Endoscopy (ESGE) held its annual congress. Professor Donnez was invited to present the results of his experience in the

  • Caesarean section scar surgery Since 2008 and its first publication on the laparoscopic treatment of caesarean section scar dehiscence, the CEC has continued its research into the diagnostic and surgical management of cases where uterine reconstruction is required. We are pleased to present our latest manuscript containing all the latest data on the subject.

  • To improve the management of patients suffering from complex endometriosis (digestive, urinary, ovarian), and to respond to the pertinent questions raised by the medical professionals who are confronted with it, the CEC now offers the possibility of requesting a specialist opinion via remote image rereading.

  • The CEC is actively involved in training healthcare professionals in conjunction with the MANOLETA patient association. A scientific presentation on endometriosis and its management took place on September 16, 2023 at the polyclinique URBAIN V in AvignonMore than 20 professionals were present and were able to exchange ideas and experiences.

  • The CEC is involved in training gynecologists, attending physicians and midwives in partnership with EDUPRAT and the MANOLETA association. Endometriosis: Never Give Up! (MANOLETA) and Teenage menorrhagia (EDUPRAT) brought together professionals from all over France.

  • The CEC is currently participating in the ENDORA 2 study in partnership with the Clermont-Ferrand University Hospital and the SURGAR company. This is the first step in the use of augmented reality allowing the surgeon to see inside the pelvic organs using a software mixing MRI imaging with

  • The CEC has set up multidisciplinary meetings that can be accessed remotely via the ROFIM platform, to enable as many specialists as possible to have access to the RCP, and to obtain a rapid opinion with an immediate RCP form. The platform can be used to download images of

  • In the medical landscape, the Endometriosis Complex Center stands out for the excellence of its expertise in the field of endometriosis treatment.
    We are not just a medical center, but an institution where the international renown of its specialists converges towards a common mission: to offer women suffering from endometriosis comprehensive and holistic care.

    Beyond medical and surgical treatments, our center advocates a human approach. Our staff, from gynecologists and surgeons to nurses and fertility specialists, are driven by an unwavering passion: to enable every woman to regain her quality of life and experience the miracle of procreation.

    In a world where information abounds, the CEC strives to denounce pseudo-expert practices that compromise women's health, and to distance itself from self-proclaimed expertise. Medical and scientific ethics are at the heart of our concerns.

    Every woman is unique, just like her disease. The CEC offers care adapted to each type of endometriosis, taking into account individual needs and specificities.
    The Complex Endometriosis Center is the promise of uncompromising expertise, dedicated to those who aspire to a better future and quality support throughout their lives.

    The CEC is the one and only center in France to master CO2 laser technology in laparoscopic surgery, a revolution in less invasive and conservative surgical treatment of endometriosis.

    The CEC's expertise is expressed in scientific publications, research results, bibliography and a strong desire to provide better support for patients suffering from endometriosis and the possibility of experiencing pregnancy.

    The purpose of our website is to inform patients about the endometriotic pathologies treated by CEC, and the specific features of our center, which has more than 20 years' experience in the use of CO2 lasers in laparoscopic surgery - the only one of its kind in France.
    The information provided is the fruit of our experience published in the scientific literature (series reviews and basic research), based on solid, reliable data.
    CEC follows the guidelines of the European Society of Human Reproduction and Embryology (ESHRE), published in February 2022.

    + 33 (0)4 90 20 00 00

    Monday to Friday from 9am to 12pm


    Please note that this address is not to be used in the case of a post-operative emergency.

    Complex Endometriosis Center

    95, chemin du Pont des 2 Eaux, on the 2nd floor of the house of Asclepius.

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